What's the relationship between physical and mental pain, and how can you ease both? Revealing how your experiences of love, loss and pain are deeply intertwined, neuroscientist Yoram Yovell sheds light on the surprising role of your brain's endorphins and opioid receptors to ease physical and emotional suffering — and shows how this connection could pave the way to new treatments for mental health and well-being.

Biomedical researcher Sonia Vallabh's life was turned upside down when she learned she had the genetic mutation for a rare and fatal illness, prion disease, that could strike at any time. Thirteen years later, her search for a cure has led to new insights about how to catch and prevent disease — and how to honor our grandest, most mysterious inheritance: our brains.

What if you could transform your anxiety into something you can actually use during your work day? This week, we're revisiting a talk by neuroscientist Wendy Suzuki, who shares two evidence-based activities — breathing and movement — that can soothe your nervous system and fuel creativity and connection.

What you experience through your senses — sight, smell, hearing, taste and touch — can impact how healthy you are and how long you live, says neurobiologist Christi Gendron. She explores how environmental cues like temperature, light and even just the sight of death have influenced the lifespan of fruit flies, suggesting your everyday perceptions may have direct repercussions on your ability to live a long, healthy life.

Here's a conundrum: the same aerosol pollutants that harm human health also help cool the climate, says atmospheric scientist Sarah J. Doherty. Is there a way to clean up the air without warming the planet? Exploring the unintended consequences of reducing air pollution, she makes the case for a better understanding of marine cloud brightening — or intentionally adding sea salt aerosols to clouds over the ocean, which could reflect sunlight back into space and potentially reduce global warming.

Countries around the world waste huge amounts of food every year: roughly a fifth of food items in the US are tossed because consumers aren't sure how to interpret expiration labels. But most groceries are still perfectly safe to eat past their expiration dates. If the dates on our food don't tell us that something's gone bad, what do they tell us? Carolyn Beans shares how to prevent food waste. This TED-Ed lesson was directed by Anton Bogaty, narrated by Alexandra Panzer and the music is by Salil Bhayani, cAMP Studio.

Organ transplants save lives, but they come with challenges: every minute a healthy donated organ is on ice increases risk. And even if things go perfectly, rejection of the organ is still possible. Cardiothoracic surgeon Abbas Ardehali introduces cutting-edge medical advances in machine perfusion — a portable platform that keeps organs alive outside of the body — that could help put time back on the patient's side.

"Everybody pees and poops — and we know that urine and stool contain a rich source of information on our health," says data detective Newsha Ghaeli. Exploring the growing field of wastewater epidemiology, she shows how studying sewage can (anonymously) reveal a lot about the collective well-being of our cities — leading to real-time quality-of-life improvements like tracking pandemics, updating social policies and much more.

On average, adults catch more than 150 colds throughout their lives. Even with similar symptoms, the cause could be different each time. Common colds are caused by at least 8 different families of virus, each of which can have its own subtypes. How can so many different viruses cause the same illness? And is a cure even possible? Explore the two main strategies we employ to fight viruses. This TED-Ed lesson was directed by Anton Bogaty, narrated by George Zaidan and the music is by Nikola Radivojevic.

Menopause isn't just hot flashes, says gynecologist and sexual medicine specialist Maria Sophocles. It's often accompanied by overlooked symptoms like painful sex or loss of libido. Shedding light on what she calls the "bedroom gap," or the difference in sexual expectations of men and women in midlife due to societal norms, Sophocles advocates for education, medical advancement and a new understanding of menopause — because sex should be pleasurable and comfortable for everyone. After the talk, join Shoshana for a conversation with OB/GYN and women’s health advocate Dr. Jessica Shepherd.

Everything our bodies do— whether physical or mental— uses energy. Studies have found that many individuals seem to have a daily threshold for making decisions, and an extended period of decision-making can lead to cognitive exhaustion. So, what kinds of choices lead us to this state, and what can we do to fight fatigue? Explore the psychology of decision fatigue and ways you can avoid fatigue. Directed by Jolene Tan, narrated by Alexandra Panzer and music by Jeremie Lim.